TransPennine Express (TPE) is a British train operating company owned by FirstGroup that operates the TransPennine Express franchise. It runs regional and inter-city rail services between the major cities and towns of Northern England and Scotland.

The franchise operates all its services to and through Manchester covering three main routes. The service provides rail links for major towns and cities such as Edinburgh, Glasgow, Liverpool, Sheffield, Hull, Leeds, York, Scarborough, Middlesbrough and Newcastle. TPE also run trains 24 hours a day, including through New Year’s Eve night. TPE trains run between York, Leeds and Manchester Airport at least every three hours every night of the week. The franchise operates across the West Coast Main Line, Huddersfield Line, East Coast Main Line and part of the Tees Valley line.